Desyrel, or generic Desyrel (trazodone), is an anti-depressant, a medicine which helps in the lifting of mental depression. The drug could help people whose depression hasn’t responded to other medicines, or those who have experienced limited side effects with other anti-depressants. Desyrel could also be used for the treatment of other conditions such as panic attacks, anxiety and sleeping disorders.
Trazodone in Desyrel acts mostly like a 5-HT2A reception antagonist for mediating its therapeutic benefits. The drugs inhibitory effects the 5-HT2C receptors and serotonin reuptake are comparatively weak i.e. ~15-fold lesser than against 5-HT2C, and contribute marginally to the overall effects. Hence, trazodone doesn’t have similar properties like SSRIs i.e. selective serotonin reuptake inhibitors and isn’t particularly associated to weight gain and increased appetite, unlike any other 5-HT2C antagonist like mirtazapine.